Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies
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چکیده
منابع مشابه
Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies
Spatial regulation of exocytosis relies on the exocyst, a hetero-octameric protein complex that tethers vesicles to fusion sites at the plasma membrane. Nevertheless, our understanding of mechanisms regulating exocyst assembly/disassembly, localization, and function are incomplete. Here, we have exploited a panel of anti-Sec6 monoclonal antibodies (mAbs) to probe possible configurational change...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2016
ISSN: 2296-634X
DOI: 10.3389/fcell.2016.00051